{"id":17206,"date":"2026-02-13T17:21:45","date_gmt":"2026-02-13T16:21:45","guid":{"rendered":"https:\/\/www.cbd.fr\/blog\/?p=17206"},"modified":"2026-02-13T17:21:46","modified_gmt":"2026-02-13T16:21:46","slug":"cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients","status":"publish","type":"post","link":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/","title":{"rendered":"CBD and Salbutamol\/Albuterol: A combination to explore for asthmatic patients?"},"content":{"rendered":"<p>Cannabidiol (CBD) is a non-psychoactive component of cannabis that is generating increasing interest in the health world. Its anti-inflammatory and relaxing properties could potentially help people with asthma. Salbutamol, or albuterol, is already widely used to treat asthma and relieve asthma attacks. In this article, we will examine the interactions between these two substances and their influence on this chronic condition. <strong>Medications Using Salbutamol\/Albuterol<\/strong> Salbutamol (also called albuterol) belongs to the class of medications called fast-acting bronchodilators. It works by relaxing the muscles around the airways to allow for easier breathing. In France, it is sold under the brand names:<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Sommaire<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #43b981;color:#43b981\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #43b981;color:#43b981\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#Ventolin\" >Ventolin<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#Extracted_from_cannabis_and_not_producing_a_psychotropic_effect_in_users_CBD_is_gaining_popularity_for_its_medicinal_properties_and_its_ability_to_improve_the_quality_of_life_for_patients_with_various_chronic_health_conditions_In_general_CBD_is_known_to\" >Extracted from cannabis and not producing a psychotropic effect in users, CBD is gaining popularity for its medicinal properties and its ability to improve the quality of life for patients with various chronic health conditions. In general, CBD is known to:<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#Have_anti-inflammatory_properties\" >Have anti-inflammatory properties<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#At_least_on_paper_there_are_no_major_contraindications_between_using_CBD_and_salbutamol_or_albuterol_together_although_no_clinical_studies_have_definitively_confirmed_that_this_combination_is_safe_However_we_already_know_that\" >At least on paper, there are no major contraindications between using CBD and salbutamol (or albuterol) together, although no clinical studies have definitively confirmed that this combination is safe. However, we already know that:<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#No_negative_drug_interactions_have_been_reported_in_the_literature_when_these_two_substances_are_used_together\" >No negative drug interactions have been reported in the literature when these two substances are used together.<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#It_is_also_essential_not_to_smoke_cannabis_to_obtain_the_medicinal_properties_of_CBD\" >It is also essential not to smoke cannabis to obtain the medicinal properties of CBD.<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#The_debate_surrounding_the_legitimacy_of_combining_CBD_and_salbutamolalbuterol_in_asthma_treatment_remains_open_However_in_France_as_in_several_countries_where_medical_cannabis_is_legal_some_doctors_are_beginning_to_incorporate_this_innovative_approach_to_alleviate_certain_problems_associated_with_the_disease_Caution_is_still_advised_when_exploring_a_new_treatment_option_consult_your_doctor_before_taking_any_action\" >The debate surrounding the legitimacy of combining CBD and salbutamol\/albuterol in asthma treatment remains open. However, in France, as in several countries where medical cannabis is legal, some doctors are beginning to incorporate this innovative approach to alleviate certain problems associated with the disease. Caution is still advised when exploring a new treatment option: consult your doctor before taking any action.<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Ventolin\"><\/span>Ventolin<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>SalbuHEXAL<\/p>\n<ul>\n<li>Sultanol<\/li>\n<li>It is also available in generic form and can be prescribed by your doctor to treat or prevent wheezing, coughing, and shortness of breath caused by asthma. ProAir: Another Name for Albuterol in the United States<\/li>\n<li>In the United States, albuterol is also marketed under the name ProAir. Used as a dose-controlled inhaler, it delivers the substance directly to the lungs for rapid action and few undesirable side effects.<\/li>\n<\/ul>\n<p>CBD: An Alternative Treatment for Asthma?<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Extracted_from_cannabis_and_not_producing_a_psychotropic_effect_in_users_CBD_is_gaining_popularity_for_its_medicinal_properties_and_its_ability_to_improve_the_quality_of_life_for_patients_with_various_chronic_health_conditions_In_general_CBD_is_known_to\"><\/span>Extracted from cannabis and not producing a psychotropic effect in users, CBD is gaining popularity for its medicinal properties and its ability to improve the quality of life for patients with various chronic health conditions. In general, CBD is known to:<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Act on the endocannabinoid system<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Have_anti-inflammatory_properties\"><\/span>Have anti-inflammatory properties<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Relieve pain<\/p>\n<ul>\n<li>Combat anxiety and sleep disorders <\/li>\n<li>Reduce certain seizures in epileptic patients<\/li>\n<li>How does CBD affect asthma?<\/li>\n<li>Studies suggest that CBD may have several beneficial effects on asthma due to its relaxing and anti-inflammatory properties. First, CBD can reduce inflammation in the airways, which can improve the comfort of asthma patients. Additionally, CBD also appears to relax the muscles around the bronchi, which could make breathing easier. Finally, CBD&#8217;s anxiolytic properties may help alleviate some psychological symptoms associated with asthma, such as anxiety or stress.<\/li>\n<li>Interactions between CBD and Salbutamol\/Albuterol<\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"At_least_on_paper_there_are_no_major_contraindications_between_using_CBD_and_salbutamol_or_albuterol_together_although_no_clinical_studies_have_definitively_confirmed_that_this_combination_is_safe_However_we_already_know_that\"><\/span>At least on paper, there are no major contraindications between using CBD and salbutamol (or albuterol) together, although no clinical studies have definitively confirmed that this combination is safe. However, we already know that:<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>CBD may potentiate certain effects of salbutamoland\/albuterol through synergy due to its various actions.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"No_negative_drug_interactions_have_been_reported_in_the_literature_when_these_two_substances_are_used_together\"><\/span>No negative drug interactions have been reported in the literature when these two substances are used together.<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Some people with asthma report feeling better thanks to CBD, either alone or in combination with their usual medications.<\/p>\n<ul>\n<li><\/li>\n<li>Some precautions to take:<\/li>\n<li>Before considering adding CBD to your asthma treatment, it is essential to consult your doctor. They can inform you about any potential risks based on your medical history and monitor your health during the combined use of these substances.<\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"It_is_also_essential_not_to_smoke_cannabis_to_obtain_the_medicinal_properties_of_CBD\"><\/span>It is also essential not to smoke cannabis to obtain the medicinal properties of CBD.<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Because burning cannabis creates and inhales numerous irritants that can worsen respiratory conditions, it&#8217;s best to opt for traditional methods like oils or <a href=\"https:\/\/www.cbd.fr\/173gelules-cbd\" data-internallinksmanager029f6b8e52c=\"8\" title=\"G\u00e9lule CBD\">capsules<\/a> to enjoy the potential benefits of CBD without the added risk to your lungs.<\/p>\n<p><strong><\/strong>In short: what about CBD and Salbutamol\/Albuterol for treating asthma?<\/p>\n<h2><span class=\"ez-toc-section\" id=\"The_debate_surrounding_the_legitimacy_of_combining_CBD_and_salbutamolalbuterol_in_asthma_treatment_remains_open_However_in_France_as_in_several_countries_where_medical_cannabis_is_legal_some_doctors_are_beginning_to_incorporate_this_innovative_approach_to_alleviate_certain_problems_associated_with_the_disease_Caution_is_still_advised_when_exploring_a_new_treatment_option_consult_your_doctor_before_taking_any_action\"><\/span>The debate surrounding the legitimacy of combining CBD and salbutamol\/albuterol in asthma treatment remains open. However, in France, as in several countries where medical cannabis is legal, some doctors are beginning to incorporate this innovative approach to alleviate certain problems associated with the disease. Caution is still advised when exploring a new treatment option: consult your doctor before taking any action.<span class=\"ez-toc-section-end\"><\/span><\/h2><\/p>\n\n\n<div class=\"kk-star-ratings kksr-auto kksr-align-left kksr-valign-bottom\"\n    data-payload='{&quot;align&quot;:&quot;left&quot;,&quot;id&quot;:&quot;17206&quot;,&quot;slug&quot;:&quot;default&quot;,&quot;valign&quot;:&quot;bottom&quot;,&quot;ignore&quot;:&quot;&quot;,&quot;reference&quot;:&quot;auto&quot;,&quot;class&quot;:&quot;&quot;,&quot;count&quot;:&quot;0&quot;,&quot;legendonly&quot;:&quot;&quot;,&quot;readonly&quot;:&quot;&quot;,&quot;score&quot;:&quot;0&quot;,&quot;starsonly&quot;:&quot;&quot;,&quot;best&quot;:&quot;5&quot;,&quot;gap&quot;:&quot;5&quot;,&quot;greet&quot;:&quot;Notez cet article&quot;,&quot;legend&quot;:&quot;0\\\/5 - (0 vote)&quot;,&quot;size&quot;:&quot;24&quot;,&quot;title&quot;:&quot;CBD and Salbutamol\\\/Albuterol: A combination to explore for asthmatic patients?&quot;,&quot;width&quot;:&quot;0&quot;,&quot;_legend&quot;:&quot;{score}\\\/{best} - ({count} {votes})&quot;,&quot;font_factor&quot;:&quot;1.25&quot;}'>\n            \n<div class=\"kksr-stars\">\n    \n<div class=\"kksr-stars-inactive\">\n            <div class=\"kksr-star\" data-star=\"1\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"2\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"3\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"4\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"5\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n    <\/div>\n    \n<div class=\"kksr-stars-active\" style=\"width: 0px;\">\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n    <\/div>\n<\/div>\n                \n\n<div class=\"kksr-legend\" style=\"font-size: 19.2px;\">\n            <span class=\"kksr-muted\">Notez cet article<\/span>\n    <\/div>\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Cannabidiol (CBD) is a non-psychoactive component of cannabis that is generating increasing interest in the health world. Its anti-inflammatory and relaxing properties could potentially help people with asthma. Salbutamol, or albuterol, is already widely used to treat asthma and relieve asthma attacks. In this article, we will examine the interactions between these two substances and [&hellip;]<\/p>\n","protected":false},"author":90,"featured_media":12078,"comment_status":"closed","ping_status":"open","sticky":false,"template":"default\n","format":"standard","meta":{"_sitemap_exclude":false,"_sitemap_priority":"","_sitemap_frequency":"","footnotes":""},"categories":[999],"tags":[],"class_list":["post-17206","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sante-et-cbd-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>CBD and Salbutamol\/Albuterol: A combination to explore for asthmatic patients? - CBD Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\ud83c\udf31CBD and Salbutamol\/Albuterol: A combination to explore for asthmatic patients? - CBD.fr \ud83c\udf31\" \/>\n<meta property=\"og:description\" content=\"Cannabidiol (CBD) is a non-psychoactive component of cannabis that is generating increasing interest in the health world. Its anti-inflammatory and relaxing properties could potentially help people with asthma. Salbutamol, or albuterol, is already widely used to treat asthma and relieve asthma attacks. In this article, we will examine the interactions between these two substances and [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/\" \/>\n<meta property=\"og:site_name\" content=\"CBD Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/cbdfrr\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-02-13T16:21:45+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-13T16:21:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.cbd.fr\/blog\/wp-content\/uploads\/2024\/03\/le-cbd-et-le-salbutamolalbuterol-une-combinaison-a-explorer-pour-les-patients-asthmatiques.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1456\" \/>\n\t<meta property=\"og:image:height\" content=\"832\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Julien\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Julien\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"CBD and Salbutamol\/Albuterol: A combination to explore for asthmatic patients? - CBD Blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/","og_locale":"fr_FR","og_type":"article","og_title":"\ud83c\udf31CBD and Salbutamol\/Albuterol: A combination to explore for asthmatic patients? - CBD.fr \ud83c\udf31","og_description":"Cannabidiol (CBD) is a non-psychoactive component of cannabis that is generating increasing interest in the health world. Its anti-inflammatory and relaxing properties could potentially help people with asthma. Salbutamol, or albuterol, is already widely used to treat asthma and relieve asthma attacks. In this article, we will examine the interactions between these two substances and [&hellip;]","og_url":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/","og_site_name":"CBD Blog","article_publisher":"https:\/\/www.facebook.com\/cbdfrr\/","article_published_time":"2026-02-13T16:21:45+00:00","article_modified_time":"2026-02-13T16:21:46+00:00","og_image":[{"width":1456,"height":832,"url":"https:\/\/www.cbd.fr\/blog\/wp-content\/uploads\/2024\/03\/le-cbd-et-le-salbutamolalbuterol-une-combinaison-a-explorer-pour-les-patients-asthmatiques.jpg","type":"image\/jpeg"}],"author":"Julien","twitter_card":"summary_large_image","twitter_misc":{"\u00c9crit par":"Julien","Dur\u00e9e de lecture estim\u00e9e":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#article","isPartOf":{"@id":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/"},"author":{"name":"Julien","@id":"https:\/\/www.cbd.fr\/blog\/#\/schema\/person\/d78b472d184ec8ae4135d454e3338c04"},"headline":"CBD and Salbutamol\/Albuterol: A combination to explore for asthmatic patients?","datePublished":"2026-02-13T16:21:45+00:00","dateModified":"2026-02-13T16:21:46+00:00","mainEntityOfPage":{"@id":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/"},"wordCount":585,"publisher":{"@id":"https:\/\/www.cbd.fr\/blog\/#organization"},"image":{"@id":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/#primaryimage"},"thumbnailUrl":"https:\/\/www.cbd.fr\/blog\/wp-content\/uploads\/2024\/03\/le-cbd-et-le-salbutamolalbuterol-une-combinaison-a-explorer-pour-les-patients-asthmatiques.jpg","articleSection":["Sant\u00e9 et CBD"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/","url":"https:\/\/www.cbd.fr\/blog\/cbd-and-salbutamol-albuterol-a-combination-to-explore-for-asthmatic-patients\/","name":"CBD and Salbutamol\/Albuterol: A combination to explore for asthmatic patients? 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