{"id":17352,"date":"2026-02-13T17:26:39","date_gmt":"2026-02-13T16:26:39","guid":{"rendered":"https:\/\/www.cbd.fr\/blog\/?p=17352"},"modified":"2026-02-13T17:26:40","modified_gmt":"2026-02-13T16:26:40","slug":"cbd-and-atomoxetine-a-study-of-the-interactions-between-the-substances","status":"publish","type":"post","link":"https:\/\/www.cbd.fr\/blog\/en\/cbd-and-atomoxetine-a-study-of-the-interactions-between-the-substances\/","title":{"rendered":"CBD and Atomoxetine: a study of the interactions between the substances"},"content":{"rendered":"<p>The popularity of CBD (cannabidiol) continues to grow worldwide due to its numerous health benefits. At the same time, atomoxetine, also known by the brand names Strattera and Attentin, is a frequently prescribed medication for the treatment of attention deficit hyperactivity disorder (ADHD). This article explores the potential interactions between CBD and atomoxetine, as well as their combined effects on patients. <strong>CBD: A Compound with Multiple Therapeutic Actions<\/strong> CBD is a non-psychoactive cannabinoid extracted from the cannabis plant. Unlike <a href=\"https:\/\/www.cbd.fr\/198thccbd\" data-internallinksmanager029f6b8e52c=\"17\" title=\"thc - t\u00e9trahydrocannabinol\">THC<\/a> (tetrahydrocannabinol), it does not produce a euphoric effect and has a range of diverse therapeutic actions. CBD has been studied for its potential beneficial effects in treating numerous conditions, such as:<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Sommaire<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #43b981;color:#43b981\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #43b981;color:#43b981\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.cbd.fr\/blog\/en\/cbd-and-atomoxetine-a-study-of-the-interactions-between-the-substances\/#Anxiety_and_depressive_disorders\" >Anxiety and depressive disorders<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.cbd.fr\/blog\/en\/cbd-and-atomoxetine-a-study-of-the-interactions-between-the-substances\/#Like_all_medications_atomoxetine_can_cause_side_effects_in_some_patients_Common_side_effects_include\" >Like all medications, atomoxetine can cause side effects in some patients. Common side effects include:<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.cbd.fr\/blog\/en\/cbd-and-atomoxetine-a-study-of-the-interactions-between-the-substances\/#To_date_there_are_no_clinical_studies_specifically_dedicated_to_the_interactions_between_CBD_and_atomoxetine_However_some_elements_from_research_on_these_two_molecules_may\" >To date, there are no clinical studies specifically dedicated to the interactions between CBD and atomoxetine. However, some elements from research on these two molecules may<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.cbd.fr\/blog\/en\/cbd-and-atomoxetine-a-study-of-the-interactions-between-the-substances\/#CBD_has_been_studied_for_its_modulating_effect_on_several_neurotransmitter_systems_including_serotonin_and_dopamine_Preliminary_research_suggests_that_CBD_could_inhibit_norepinephrine_reuptake_a_mechanism_of_action_similar_to_that_of_atomoxetine\" >CBD has been studied for its modulating effect on several neurotransmitter systems, including serotonin and dopamine. Preliminary research suggests that CBD could inhibit norepinephrine reuptake, a mechanism of action similar to that of atomoxetine.<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.cbd.fr\/blog\/en\/cbd-and-atomoxetine-a-study-of-the-interactions-between-the-substances\/#Influence_of_CBD_on_the_hepatic_metabolism_of_atomoxetine\" >Influence of CBD on the hepatic metabolism of atomoxetine<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Anxiety_and_depressive_disorders\"><\/span>Anxiety and depressive disorders<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Chronic and inflammatory pain<\/p>\n<ul>\n<li>Epilepsy and seizures<\/li>\n<li>Sleep disorders<\/li>\n<li>Neurological disorders, such as Parkinson&#8217;s disease and multiple sclerosis<\/li>\n<li>These properties make CBD an interesting candidate for research and development of new drugs.<\/li>\n<li><\/li>\n<\/ul>\n<p>Atomoxetine: a common pharmacological treatment for ADHD <strong>Atomoxetine is a medication approved by health authorities for the<\/strong>treatment of ADHD in children, adolescents, and adults.<\/p>\n<h2><\/h2>\n<p>The molecule works by selectively inhibiting the norepinephrine transporter, which leads to an increase in the levels of this neurotransmitter in the brain. This action helps improve ADHD symptoms such as inattention, hyperactivity, and impulsivity. <strong><\/strong>Side effects of atomoxetine<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Like_all_medications_atomoxetine_can_cause_side_effects_in_some_patients_Common_side_effects_include\"><\/span>Like all medications, atomoxetine can cause side effects in some patients. Common side effects include:<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Nausea<\/p>\n<ul>\n<li>Drowsiness<\/li>\n<li>Headache<\/li>\n<li>Dizziness<\/li>\n<li>Increased blood pressure and heart rate<\/li>\n<li>These symptoms generally decrease over time and can be minimized by adjusting the dosage.<\/li>\n<\/ul>\n<p>Interactions between CBD and atomoxetine: synergistic or antagonistic potential?<\/p>\n<h2><span class=\"ez-toc-section\" id=\"To_date_there_are_no_clinical_studies_specifically_dedicated_to_the_interactions_between_CBD_and_atomoxetine_However_some_elements_from_research_on_these_two_molecules_may\"><\/span>To date, there are no clinical studies specifically dedicated to the interactions between CBD and atomoxetine. However, some elements from research on these two molecules may<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>suggest a potentially synergistic or antagonistic action when combined. <strong><\/strong>CBD&#8217;s action on neurotransmitters<\/p>\n<h3><span class=\"ez-toc-section\" id=\"CBD_has_been_studied_for_its_modulating_effect_on_several_neurotransmitter_systems_including_serotonin_and_dopamine_Preliminary_research_suggests_that_CBD_could_inhibit_norepinephrine_reuptake_a_mechanism_of_action_similar_to_that_of_atomoxetine\"><\/span>CBD has been studied for its modulating effect on several neurotransmitter systems, including serotonin and dopamine. Preliminary research suggests that CBD could inhibit norepinephrine reuptake, a mechanism of action similar to that of atomoxetine.<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Under this hypothesis, combining these two substances could potentiate their therapeutic effects by increasing norepinephrine levels in the brain. However,<\/p>\n<p>further studies are needed to confirm this hypothesis <strong>and assess the potential of such a combination in the current therapeutic landscape.<\/strong> <\/p>\n<h3><span class=\"ez-toc-section\" id=\"Influence_of_CBD_on_the_hepatic_metabolism_of_atomoxetine\"><\/span>Influence of CBD on the hepatic metabolism of atomoxetine<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>CBD is also known to interact with various hepatic enzymes of the cytochrome P450 system, which play a key role in drug metabolism. In particular, CBD can inhibit certain isoforms of these enzymes, thereby altering the metabolism and pharmacokinetics of many drugs.<\/p>\n<p>Atomoxetine is primarily metabolized by the CYP2D6 isoform of cytochrome P450. <strong>Interactions between CBD and this enzyme could therefore affect the pharmacokinetics and\/or efficacy of atomoxetine.<\/strong> Further studies are needed to assess the implications of these interactions and their impact on patients treated with atomoxetine who also use CBD.<\/p>\n<h2><\/h2>\n<p>What are the risks associated with using CBD and atomoxetine together?<\/p>\n<p>Since few studies have highlighted the potential interactions between atomoxetine and CBD, a degree of caution is recommended if they are used concurrently. Patients considering taking both substances should consult their doctor or pharmacist beforehand to obtain informed advice tailored to their specific medical situation.<\/p>\n\n\n<div class=\"kk-star-ratings kksr-auto kksr-align-left kksr-valign-bottom\"\n    data-payload='{&quot;align&quot;:&quot;left&quot;,&quot;id&quot;:&quot;17352&quot;,&quot;slug&quot;:&quot;default&quot;,&quot;valign&quot;:&quot;bottom&quot;,&quot;ignore&quot;:&quot;&quot;,&quot;reference&quot;:&quot;auto&quot;,&quot;class&quot;:&quot;&quot;,&quot;count&quot;:&quot;0&quot;,&quot;legendonly&quot;:&quot;&quot;,&quot;readonly&quot;:&quot;&quot;,&quot;score&quot;:&quot;0&quot;,&quot;starsonly&quot;:&quot;&quot;,&quot;best&quot;:&quot;5&quot;,&quot;gap&quot;:&quot;5&quot;,&quot;greet&quot;:&quot;Notez cet article&quot;,&quot;legend&quot;:&quot;0\\\/5 - (0 vote)&quot;,&quot;size&quot;:&quot;24&quot;,&quot;title&quot;:&quot;CBD and Atomoxetine: a study of the interactions between the substances&quot;,&quot;width&quot;:&quot;0&quot;,&quot;_legend&quot;:&quot;{score}\\\/{best} - ({count} {votes})&quot;,&quot;font_factor&quot;:&quot;1.25&quot;}'>\n            \n<div class=\"kksr-stars\">\n    \n<div class=\"kksr-stars-inactive\">\n            <div class=\"kksr-star\" data-star=\"1\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"2\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"3\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"4\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"5\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n    <\/div>\n    \n<div class=\"kksr-stars-active\" style=\"width: 0px;\">\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n    <\/div>\n<\/div>\n                \n\n<div class=\"kksr-legend\" style=\"font-size: 19.2px;\">\n            <span class=\"kksr-muted\">Notez cet article<\/span>\n    <\/div>\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>The popularity of CBD (cannabidiol) continues to grow worldwide due to its numerous health benefits. At the same time, atomoxetine, also known by the brand names Strattera and Attentin, is a frequently prescribed medication for the treatment of attention deficit hyperactivity disorder (ADHD). This article explores the potential interactions between CBD and atomoxetine, as well [&hellip;]<\/p>\n","protected":false},"author":90,"featured_media":12098,"comment_status":"closed","ping_status":"open","sticky":false,"template":"default\n","format":"standard","meta":{"_sitemap_exclude":false,"_sitemap_priority":"","_sitemap_frequency":"","footnotes":""},"categories":[999],"tags":[],"class_list":["post-17352","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sante-et-cbd-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.9 (Yoast SEO v26.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>CBD and Atomoxetine: a study of the interactions between the substances - CBD Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cbd.fr\/blog\/en\/cbd-and-atomoxetine-a-study-of-the-interactions-between-the-substances\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\ud83c\udf31CBD and Atomoxetine: a study of the interactions between the substances - CBD.fr \ud83c\udf31\" \/>\n<meta property=\"og:description\" content=\"The popularity of CBD (cannabidiol) continues to grow worldwide due to its numerous health benefits. At the same time, atomoxetine, also known by the brand names Strattera and Attentin, is a frequently prescribed medication for the treatment of attention deficit hyperactivity disorder (ADHD). 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