{"id":22813,"date":"2026-02-13T20:32:13","date_gmt":"2026-02-13T19:32:13","guid":{"rendered":"https:\/\/www.cbd.fr\/blog\/?p=22813"},"modified":"2026-02-13T20:32:14","modified_gmt":"2026-02-13T19:32:14","slug":"what-is-this-terpene-caryophyllene-as-seen-by-cbd-fr","status":"publish","type":"post","link":"https:\/\/www.cbd.fr\/blog\/en\/what-is-this-terpene-caryophyllene-as-seen-by-cbd-fr\/","title":{"rendered":"What is this terpene? Caryophyllene as seen by CBD.fr"},"content":{"rendered":"\n<p>Caryophyllene is a component belonging to the terpene category. In fact, it is closely related to humulene, which we discussed in a previous article. As we continue our exploration of terpenes, we&#8217;ll focus on this one. What does science say about it? What are its benefits for consumers of CBD products? Let&#8217;s delve into this further below. <strong>Science Speaks About Caryophyllene<\/strong> As always, let&#8217;s begin by examining caryophyllene from a scientific perspective. So, what does science say about this terpene?<strong> <a href=\"https:\/\/www.cbd.fr\/blog\/les-terpenes\/\" target=\"_blank\" rel=\"noreferrer noopener\">Introducing Caryophyllene<\/a><\/strong>Indeed, science also refers to it as \u03b2-caryophyllene. So, if you encounter this other term, know that it is the same thing. Furthermore, it adds that this terpene is very similar to humulene, as we mentioned earlier. In this vein, it states that caryophyllene is a naturally occurring bicyclic sesquiterpene composed of a nine-carbon macrocycle fused to a cyclobutane ring. <a href=\"https:\/\/www.cbd.fr\/\"><strong><\/strong><\/a> In simpler terms, it&#8217;s a natural terpene composed of large nine-carbon rings. It is found in many plants such as hops, hemp, rosemary, and clove. What about its uses? Science suggests that this terpene is widely used in the production of essential oils, particularly those produced by the clove tree and certain hemp oils.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"a\"><\/h2>\n\n\n\n<p>Caryophyllene and Our Bodies <strong>Let&#8217;s now try to understand how this terpene interacts with our bodies. According to science, this compound tends to act similarly to its cousins, the cannabinoids. How can this be explained? It interacts with the endocannabinoid system.<\/strong> (ECS). From this perspective, for your information, the ECS refers to a network or set of receptors present in various organs of the body. The best-known receptors are CB1 and CB2. That being said, caryophyllene does not bind to CB1. However, it interacts with CB2. This allows it to exert its anti-inflammatory effect within the body.<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Sommaire<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #43b981;color:#43b981\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #43b981;color:#43b981\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.cbd.fr\/blog\/en\/what-is-this-terpene-caryophyllene-as-seen-by-cbd-fr\/#Caryophyllene_for_CBD_Product_Users\" >Caryophyllene for CBD Product Users<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.cbd.fr\/blog\/en\/what-is-this-terpene-caryophyllene-as-seen-by-cbd-fr\/#Therapeutic_Interest\" >Therapeutic Interest<\/a><\/li><\/ul><\/nav><\/div>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Caryophyllene_for_CBD_Product_Users\"><\/span>Caryophyllene for CBD Product Users<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Since we have already highlighted the scientific perspective of this terpene, let&#8217;s return to a point that could be of great interest to CBD product users. <strong>The Aromatic Appeal<\/strong>Let&#8217;s start with this characteristic that most terpenes have in common. Indeed, this component has a unique taste and smell. In fact, its aromas are similar to those of pepper, spices, and cloves. So, if you have ever used any of the aforementioned ingredients, you will find it very easy to identify this terpene. Especially since it is generally present in large quantities in the plants. Therefore, its aromas tend to dominate others.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Therapeutic_Interest\"><\/span>Therapeutic Interest<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Indeed, the components present in the hemp\/cannabis plant are rarely devoid of therapeutic properties. In this regard, our current terpene is no exception. In fact, it is said to have antioxidant, neuroprotective, antimicrobial, gastroprotective, anticonvulsant, analgesic, and anti-inflammatory effects. Furthermore, it could also be useful in treating alcoholism. Let&#8217;s review some related research\/studies. <a href=\"https:\/\/www.cbd.fr\/blog\/quest-ce-que-le-systeme-endocannabinoide\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a> An animal study published in the journal Physiology &amp; Behavior highlights the fact that this terpene could help relieve anxiety and depression. Indeed, researchers conducted tests on mice, which measure mental distress, anxiety, and depression. The results show that administration of <strong>Caryophyllene may reduce levels of anxiety, depression, and compulsive behaviors. Researchers attribute this to the fact that, as mentioned earlier, the terpene binds to the CB2 receptor, which is closely linked to anxiety and depression.<\/strong> Research published in the journal *Pharmacology Biochemistry and Behavior* explores the possibility that this compound could help with alcoholism. In fact, the biggest challenge in these cases is usually breaking the vicious cycle of alcohol addiction. This research suggests that CB2 receptors in the brain could be useful in this fight. To test this, researchers conducted tests on rodents. They gave the mice alcohol to drink and then injected them with caryophyllene. They subsequently discovered that the rodents voluntarily reduced their alcohol consumption. To further confirm this, they administered CB2 receptor blockers. The question was whether the mice changed their behavior. Indeed, they started drinking alcohol again. The researchers concluded that this terpene could be used to treat alcoholism.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"b\"><\/h2>\n\n\n\n<p>A study published in the journal *European Neuropsychopharmacology* in 2014 focused on its anti-inflammatory, analgesic, and neuroprotective effects. It showed that this terpene could reduce inflammation in the terminal phase. Furthermore, it highlighted that, with regard to neuropathic pain, caryophyllene reduced the heat caused by temperature and neuroinflammation of the spinal cord.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<p>A study published in *Epilepsy &amp; Behavior* explained that a dose of this terpene reduced seizures in mice. Therefore, this anticonvulsant property could be used in humans.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><\/h3>\n\n\n\n<p>Also, see our article on the terpene humulene.<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><span style=\"text-decoration: underline\">References <em>https:\/\/fr.wikipedia.org\/wiki\/Caryophyll%C3%A8ne<\/em><\/span> https:\/\/www.cibdol.fr\/encyclopedie-du-cbd\/qu-est-ce-que-le-caryophyll%C3%A8ne <strong>https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24930711<\/strong> https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091305714001956<\/li>\n\n\n\n<li><span style=\"text-decoration: underline\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1525505015006952 <em><\/em><\/span>  <strong><\/strong><\/li>\n\n\n\n<li><span style=\"text-decoration: underline\"> <em><\/em>  <\/span>  <strong><\/strong> <\/li>\n\n\n\n<li><span style=\"text-decoration: underline\"> <em><\/em><\/span> <\/li>\n<\/ol>\n\n\n\n<p> <strong><a href=\"https:\/\/www.cbd.fr\/blog\/en-savoir-plus-sur-les-terpenes-lhumulene\/\"><\/a><\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-css-opacity\">\n\n\n\n<p><span style=\"text-decoration: underline\"><\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><\/li>\n\n\n\n<li><\/li>\n\n\n\n<li><\/li>\n\n\n\n<li><\/li>\n\n\n\n<li><\/li>\n<\/ul>\n\n\n\n<div class=\"kk-star-ratings kksr-auto kksr-align-left kksr-valign-bottom\"\n    data-payload='{&quot;align&quot;:&quot;left&quot;,&quot;id&quot;:&quot;22813&quot;,&quot;slug&quot;:&quot;default&quot;,&quot;valign&quot;:&quot;bottom&quot;,&quot;ignore&quot;:&quot;&quot;,&quot;reference&quot;:&quot;auto&quot;,&quot;class&quot;:&quot;&quot;,&quot;count&quot;:&quot;0&quot;,&quot;legendonly&quot;:&quot;&quot;,&quot;readonly&quot;:&quot;&quot;,&quot;score&quot;:&quot;0&quot;,&quot;starsonly&quot;:&quot;&quot;,&quot;best&quot;:&quot;5&quot;,&quot;gap&quot;:&quot;5&quot;,&quot;greet&quot;:&quot;Notez cet article&quot;,&quot;legend&quot;:&quot;0\\\/5 - (0 vote)&quot;,&quot;size&quot;:&quot;24&quot;,&quot;title&quot;:&quot;What is this terpene? Caryophyllene as seen by CBD.fr&quot;,&quot;width&quot;:&quot;0&quot;,&quot;_legend&quot;:&quot;{score}\\\/{best} - ({count} {votes})&quot;,&quot;font_factor&quot;:&quot;1.25&quot;}'>\n            \n<div class=\"kksr-stars\">\n    \n<div class=\"kksr-stars-inactive\">\n            <div class=\"kksr-star\" data-star=\"1\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"2\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"3\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"4\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"5\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n    <\/div>\n    \n<div class=\"kksr-stars-active\" style=\"width: 0px;\">\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n    <\/div>\n<\/div>\n                \n\n<div class=\"kksr-legend\" style=\"font-size: 19.2px;\">\n            <span class=\"kksr-muted\">Notez cet article<\/span>\n    <\/div>\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Caryophyllene is a component belonging to the terpene category. In fact, it is closely related to humulene, which we discussed in a previous article. As we continue our exploration of terpenes, we&#8217;ll focus on this one. What does science say about it? What are its benefits for consumers of CBD products? Let&#8217;s delve into this [&hellip;]<\/p>\n","protected":false},"author":90,"featured_media":4789,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_sitemap_exclude":false,"_sitemap_priority":"","_sitemap_frequency":"","footnotes":""},"categories":[970],"tags":[],"class_list":["post-22813","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-cannabis-et-cbd-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.9 (Yoast SEO v26.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What is this terpene? Caryophyllene as seen by CBD.fr - CBD Blog<\/title>\n<meta name=\"description\" content=\"Caryophyllene is a terpene. What does science say about it? What are its benefits for consumers of CBD products?\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cbd.fr\/blog\/en\/what-is-this-terpene-caryophyllene-as-seen-by-cbd-fr\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\ud83c\udf31What is this terpene? Caryophyllene as seen by CBD.fr - CBD.fr \ud83c\udf31\" \/>\n<meta property=\"og:description\" content=\"Caryophyllene is a terpene. What does science say about it? 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What are its benefits for consumers of CBD products?","og_url":"https:\/\/www.cbd.fr\/blog\/en\/what-is-this-terpene-caryophyllene-as-seen-by-cbd-fr\/","og_site_name":"CBD Blog","article_publisher":"https:\/\/www.facebook.com\/cbdfrr\/","article_published_time":"2026-02-13T19:32:13+00:00","article_modified_time":"2026-02-13T19:32:14+00:00","og_image":[{"width":740,"height":500,"url":"https:\/\/www.cbd.fr\/blog\/wp-content\/uploads\/2021\/05\/Terpene_Caryophyllene.jpg","type":"image\/jpeg"}],"author":"Julien","twitter_card":"summary_large_image","twitter_misc":{"\u00c9crit par":"Julien","Dur\u00e9e de lecture estim\u00e9e":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.cbd.fr\/blog\/en\/what-is-this-terpene-caryophyllene-as-seen-by-cbd-fr\/#article","isPartOf":{"@id":"https:\/\/www.cbd.fr\/blog\/en\/what-is-this-terpene-caryophyllene-as-seen-by-cbd-fr\/"},"author":{"name":"Julien","@id":"https:\/\/www.cbd.fr\/blog\/#\/schema\/person\/d78b472d184ec8ae4135d454e3338c04"},"headline":"What is this terpene? 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