{"id":8459,"date":"2023-07-25T18:56:46","date_gmt":"2023-07-25T16:56:46","guid":{"rendered":"https:\/\/www.cbd.fr\/blog\/?p=8459"},"modified":"2024-01-09T18:41:26","modified_gmt":"2024-01-09T17:41:26","slug":"etats-unis-la-consommation-de-cannabis-modifierait-lexpression-des-genes","status":"publish","type":"post","link":"https:\/\/www.cbd.fr\/blog\/etats-unis-la-consommation-de-cannabis-modifierait-lexpression-des-genes\/","title":{"rendered":"\u00c9tats-Unis\u00a0: la consommation de cannabis modifierait l\u2019expression des g\u00e8nes"},"content":{"rendered":"\n

Des chercheurs am\u00e9ricains ont visualis\u00e9 de nombreux changements \u00e9pig\u00e9n\u00e9tiques<\/strong> dans le sang des consommateurs de cannabis. Les r\u00e9sultats obtenus pourraient expliquer les infections<\/strong> et certains troubles mentaux<\/strong>, m\u00eame si d\u2019autres \u00e9tudes devront prouver un lien de causalit\u00e9.<\/p>\n\n\n\n

Une nouvelle \u00e9tude sugg\u00e8re que la consommation de cannabis peut entra\u00eener des modifications \u00e9pig\u00e9n\u00e9tiques du g\u00e9nome<\/h2>\n\n\n\n

Des chercheurs d\u2019universit\u00e9s am\u00e9ricaines ont constat\u00e9 de nombreux changements \u00e9pig\u00e9n\u00e9tiques dans le sang appartenant aux consommateurs de cannabis. Les r\u00e9sultats obtenus pourraient expliquer l\u2019origine des infections et certains troubles mentaux, m\u00eame si d\u2019autres \u00e9tudes plus approfondies devront prouver un lien de causalit\u00e9.<\/p>\n\n\n\n

Une nouvelle \u00e9tude au long court r\u00e9alis\u00e9 sur un \u00e9chantillon de plus de 1000 adultes<\/strong> sugg\u00e8re que la consommation de cannabis peut engendrer des modifications \u00e9pig\u00e9n\u00e9tiques du g\u00e9nome<\/strong>. L\u2019\u00e9pig\u00e9n\u00e9tique n\u2019alt\u00e8re pas la s\u00e9quence d\u2019ADN<\/strong>, mais r\u00e9gule plut\u00f4t l\u2019activit\u00e9 des g\u00e8nes par activation <\/strong>ou d\u00e9sactivation<\/strong>, ce qui modifier le fonctionnement du corps.   <\/p>\n\n\n\n

L\u2019ajout ou le retrait de groupes m\u00e9thyles<\/strong> de l\u2019ADN est l\u2019une des modifications \u00e9pig\u00e9n\u00e9tiques les plus \u00e9tudi\u00e9es.<\/p>\n\n\n\n

D\u2019apr\u00e8s le professeur Lifang Hou<\/strong>, \u00e9pid\u00e9miologiste op\u00e9rant \u00e0 la facult\u00e9 de m\u00e9decine am\u00e9ricaine Feinberg de l\u2019universit\u00e9 Northwestern<\/strong> : \u00ab Nous avions d\u00e9j\u00e0 identifi\u00e9 des associations entre la consommation de marijuana<\/strong> (compos\u00e9 de feuilles de cannabis) et le processus de vieillissement tel qu\u2019il est appr\u00e9hend\u00e9 par la m\u00e9thylation de l\u2019ADN.<\/p>\n\n\n\n

Nous voulions ensuite examiner si les facteurs \u00e9pig\u00e9n\u00e9tiques sp\u00e9cifiques \u00e9taient associ\u00e9s \u00e0 la consommation de marijuana et si ces facteurs \u00e9taient li\u00e9s \u00e0 des r\u00e9sultats en mati\u00e8re de sant\u00e9 \u00bb.
Les chercheurs ont analys\u00e9 des \u00e9chantillons de sang contenant des biomarqueurs <\/strong>qui permettent notamment de visualiser les m\u00e9thylations de l\u2019ADN.<\/p>\n\n\n\n

Un millier de participants dont l\u2019\u00e2ge est compris entre 18 et 30 ans<\/strong> au d\u00e9but de l\u2019\u00e9tude ont fourni ces \u00e9chantillons \u00e0 deux reprises, et ceci, sur une p\u00e9riode de 20 ans.<\/p>\n\n\n\n

Dans les \u00e9chantillons sanguins pr\u00e9lev\u00e9s apr\u00e8s 15 ans,<\/strong> pas moins de 22 marqueurs<\/strong> de m\u00e9thylation de l\u2019ADN \u00e9taient associ\u00e9s \u00e0 une consommation de cannabis r\u00e9cente et 31<\/strong> \u00e0 une consommation cumul\u00e9e de cannabis.<\/p>\n\n\n\n

Dans ceux qui avaient \u00e9t\u00e9 pr\u00e9lev\u00e9s apr\u00e8s 20 ans, les chercheurs ont trouv\u00e9 132 marqueurs<\/strong> li\u00e9s \u00e0 une consommation r\u00e9cente et 16<\/strong> \u00e0 une consommation cumulative.<\/p>\n\n\n\n

D\u2019apr\u00e8s les pr\u00e9cisions de l\u2019\u00e9pid\u00e9miologiste : \u00ab La plupart des changements \u00e9pig\u00e9n\u00e9tiques ont \u00e9t\u00e9 trouv\u00e9s dans des voies pr\u00e9c\u00e9demment li\u00e9es \u00e0 la prolif\u00e9ration cellulaire, \u00e0 la signalisation hormonale, aux infections et aux troubles mentaux tels que la Schizophr\u00e9nie<\/strong>, les troubles bipolaires<\/strong> et les troubles li\u00e9s \u00e0 l\u2019utilisation de substances psychoactives<\/strong> \u00bb.<\/p>\n\n\n\n

Cela sugg\u00e8re que la consommation de cannabis pourrait \u00e0 long terme causer des probl\u00e8mes de sant\u00e9, m\u00eame si pour le moment la recherche ne le prouve pas encore.<\/p>\n\n\n\n

Ces r\u00e9sultats ne sont pas \u00e0 prendre \u00e0 la l\u00e9g\u00e8re puisque ces \u00e9tudes ont \u00e9t\u00e9 men\u00e9es par de grands sp\u00e9cialistes du cannabis<\/a><\/strong>. Ils sugg\u00e8rent donc aux grands consommateurs de cannabis de bien r\u00e9fl\u00e9chir avant de se lancer dans la consommation de cannabis. Si ces derniers ne le font pas, ils risqueraient d\u2019attraper de nombreuses maladies li\u00e9es \u00e0 la consommation de la marijuana.<\/p>\n\n\n\n

Source :                                                                                                                                                                                        <\/p>\n\n\n\n

https:\/\/www.futura-sciences.com\/sante\/actualites\/cannabis-consommation-cannabis-modifierait-expression-genes-106658<\/a><\/p>\n\n\n

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\n 4.4\/5 - (2253 votes) <\/div>\n <\/div>\n","protected":false},"excerpt":{"rendered":"

Des chercheurs am\u00e9ricains ont visualis\u00e9 de nombreux changements \u00e9pig\u00e9n\u00e9tiques dans le sang des consommateurs de cannabis. Les r\u00e9sultats obtenus pourraient expliquer les infections et certains troubles mentaux, m\u00eame si d\u2019autres \u00e9tudes devront prouver un lien de causalit\u00e9. Une nouvelle \u00e9tude sugg\u00e8re que la consommation de cannabis peut entra\u00eener des modifications \u00e9pig\u00e9n\u00e9tiques du g\u00e9nome Des chercheurs […]<\/p>\n","protected":false},"author":90,"featured_media":8466,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_sitemap_exclude":false,"_sitemap_priority":"","_sitemap_frequency":"","footnotes":""},"categories":[227],"tags":[],"class_list":["post-8459","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualite-du-cannabis"],"yoast_head":"\nLe cannabis modifirait-il notre g\u00e9n\u00e9tique ? - CBD Blog<\/title>\n<meta name=\"description\" content=\"Des chercheurs am\u00e9ricains ont visualis\u00e9 de nombreux changements \u00e9pig\u00e9n\u00e9tiques dans le sang des consommateurs de cannabis, d\u00e9couvrez tout !\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cbd.fr\/blog\/etats-unis-la-consommation-de-cannabis-modifierait-lexpression-des-genes\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\ud83c\udf31\u00c9tats-Unis\u00a0: la consommation de cannabis modifierait l\u2019expression des g\u00e8nes - CBD.fr \ud83c\udf31\" \/>\n<meta property=\"og:description\" content=\"Des chercheurs am\u00e9ricains ont visualis\u00e9 de nombreux changements \u00e9pig\u00e9n\u00e9tiques dans le sang des consommateurs de cannabis, d\u00e9couvrez tout !\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cbd.fr\/blog\/etats-unis-la-consommation-de-cannabis-modifierait-lexpression-des-genes\/\" \/>\n<meta property=\"og:site_name\" content=\"CBD Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/cbdfrr\/\" \/>\n<meta property=\"article:published_time\" content=\"2023-07-25T16:56:46+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-01-09T17:41:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.cbd.fr\/blog\/wp-content\/uploads\/2023\/07\/genetique-canabis.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1600\" \/>\n\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Julien\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Julien\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Le cannabis modifirait-il notre g\u00e9n\u00e9tique ? 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