CBD generating increasing enthusiasm in the wellness market, to the point of raising an intriguing question: Can CBD be taken on an empty stomach to maximize its benefits?
Before answering this very impactful question, it is important to demystify the subtleties of how CBD works in our body.
In this article, we will attempt to unravel the mysteries of CBD consumed on an empty stomach and then we will show you how to get the most out of it.
Bioavailability: the secret to CBD absorption
In the vast and enriching world of CBD, there is one key element that is often overlooked: bioavailability.
You are probably wondering what this enigmatic term means? In reality, bioavailability, also called absorption rate , is the speed and efficiency with which cannabinoids or other compounds from hemp enter our bloodstream.
In simpler terms, it is the extent to which a molecule like CBD can be absorbed and act on the body's bioactive sites.
The way CBD is ingested directly influences its absorption and distribution capacity.
CBD in action: an important clarification
Because it is fat-soluble, CBD is a substance that is soluble in fats and less so in water.
Therefore, it must be taken orally, sublingually, topically, or as a spray. In other words, it must be absorbed by the body to be most effective.
For example, when CBD is ingested, its components begin a long journey through the upper digestive tract.
They then take a path to reach the liver via the hepatic vein, thus establishing a first-pass effect.
The liver then intervenes to filter and break down the constituents of CBD.
The latter then returns to the body, the colon and the small intestine where it undergoes a further decomposition process.
Moreover, upon entering the bloodstream, only a tiny fraction of the active compound of CBD manages to survive (between 5 and 15%).
CBD on an empty stomach or well-fed: the question resolved
To resolve this very impactful question, we must keep in mind that the effects of CBD vary greatly depending on whether it is taken on an empty stomach or postprandially.
It is clear that CBD absorption can be influenced by various factors, including the presence of food in the stomach.
In exceptional cases, when CBD is extremely pure, 10% of this substance manages to enter the bloodstream.
This is why CBD products are formulated with oils rich in fats, in order to promote its penetration into the body.
Furthermore, in a recent study that aimed to determine the impact of food on CBD absorption, the results revealed that when the stomach is full, CBD remains in the intestines longer, thus delaying its absorption.
On the other hand, when foods rich in fats are consumed, the body may also prioritize the absorption of these lipids to promote that of CBD.
Is it beneficial to consume CBD on an empty stomach?
In light of all these discoveries, the body seems to assimilate certain substances better when they are accompanied by meals containing healthy fats.
Studies show that taking CBD with food, especially high-fat foods, increases its bioavailability. More specifically, enjoying a meal before consuming CBD allows the body to absorb a greater amount of cannabinoids.
Furthermore, consuming a meal before ingesting CBD increases the required concentration of CBD in the body.
Editor-in-Chief specializing in CBD
Julien, born on July 17, 1978, in the Paris region, is a prominent writer and expert in the field of CBD products. Following his studies, Julien developed a passion for natural remedies, including CBD. In 2022, he joined the CBD.fr team as an expert and regular contributor. Thanks to his scientific expertise and clear writing style, Julien helps demystify the complexities of CBD, while highlighting its benefits and potential applications through his articles and conference presentations.
