Cannabidiol, or CBD, is generating increasing interest in the scientific and medical communities, as well as among the general public. This molecule, found in cannabis, possesses numerous therapeutic properties without producing the psychoactive effects of its cousin, THC. Given its growing popularity, a question often arises: does CBD damage neurons? In this article, we will explore the effects of CBD on our brain, its neuroprotective properties, and the current state of scientific research on this topic. What is CBD and how does it affect our brain?
CBD is one of the many cannabinoids found in the cannabis plant. Unlike tetrahydrocannabinol (THC), the main compound responsible for the psychoactive effects of cannabis, it does not produce euphoric or hallucinogenic effects.
CBD primarily acts by interacting with the CB1 and CB2 receptors of the endocannabinoid system (ECS) present in our bodies. The ECS is involved in various bodily functions, such as regulating pain, mood, appetite, and sleep, and contributes to the proper functioning of the central and peripheral nervous systems. By binding to these receptors, CBD can exert a positive influence on these various bodily mechanisms.
CBD’s Properties on the Nervous System
CBD is being studied for a number of neurological conditions due to its anti-inflammatory and neuroprotective properties. Specifically, it has been shown that:
- CBD possesses antioxidant effects, protecting cells against damage caused by reactive oxygen species (ROS) and other free radicals that can lead to cell death, including neuronal death; it reduces brain inflammation by modulating the production of pro-inflammatory cytokines, which can contribute to the development of several neurodegenerative diseases;it acts as
- a regulator of neuronal activity notably by reducing excessive neuro-excitation and preventing seizures in patients with epilepsy;
- it promotesneurogenesis
- that is, the creation of new neurons in certain brain regions, which could be beneficial for disorders such as depression or anxiety.
Does CBD fry neurons?
Given these properties mentioned above, it would be surprising if CBD destroyed neurons. In fact,studies conducted so far show that CBD may have a protective effect on neurons
both structurally and functionally. Thus, contrary to some misconceptions, there is no scientific evidence suggesting that CBD “fries” neurons or causes brain damage.
- Research on CBD and Neurological Diseases
- Several studies have evaluated the effect of CBD in the context of various neurological diseases, including: Alzheimer’s Disease:
- Preclinical studies have shown that CBD can reduce the production of beta-amyloid proteins, responsible for the formation of senile plaques characteristic of this disease; Parkinson’s Disease:
In vitro experiments have demonstrated the protective effect of CBD on dopaminergic cells, the death of which is responsible for the motor disorders observed in patients with this condition; Multiple Sclerosis:Clinical trials conducted on animal models have shown that CBD may reduce symptoms related to inflammation and demyelination of nerve fibers in this autoimmune disease.
However,
- further research is needed to confirm these preliminary results and evaluate the effectiveness of CBD as a potential treatment for these neurodegenerative disorders.
- Does CBD have side effects on the brain?
- While studies conducted so far suggest that CBD is generally well-tolerated by most individuals, it can still cause some side effects. These include:
fatigue;
dizziness or lightheadedness;
drowsiness, especially when used in conjunction with other sedatives; changes in appetite or weight.
