CBD, or cannabidiol, is a molecule found in cannabis plants that possesses interesting medicinal properties. This compound has generated increasing interest due to its promising effects in treating various conditions, including anxiety, pain, inflammation, and nausea. In this article, we will discuss the interactions between CBD and lansoprazole, a medication commonly used to treat stomach problems such as gastroesophageal reflux disease (GERD), gastritis, and stomach ulcers. Lansoprazole-based medications: Prevacid, Lanzor, and Lansoprazole-ratiopharmLansoprazole belongs to the class of medications called proton pump inhibitors (PPIs). It works by reducing the production of stomach acid by the cells lining the stomach. Among the lansoprazole-containing medications on the market are:
Prevacid, available as delayed-release capsules or orally disintegrating tablets; Lanzor, available in capsules of various strengths; and Lansoprazole-ratiopharm, marketed as delayed-release capsules.
These medications are indicated for treating various stomach-related disorders, such as gastric and duodenal ulcers, gastroesophageal reflux disease (GERD), and gastritis. They can be prescribed for short-term or long-term treatment, depending on the condition being treated and its progression. CBD: A natural substance with numerous therapeutic benefits A molecule derived from cannabis plants, cannabidiol, better known as CBD, has become the subject of much scientific research due to its interesting medical properties: Pain relief,
- Reduction of inflammation,Reduction of anxiety and stress,
- Improved sleep,Beneficial effects on certain neurological disorders such as epilepsy and multiple sclerosis.
- Because CBD has numerous effects, it is being used by more and more people worldwide. It can be consumed in various ways, such as orally, by inhalation, topically, etc. Interactions between CBD and lansoprazole: what do the studies say?Drug interactions are a crucial topic for patients and healthcare professionals to ensure effective and safe treatment. It is essential to check for potential interactions between two substances before combining them, whether they are medications or dietary supplements.
To date, few studies have addressed the issue of interactions between CBD and proton pump inhibitors such as lansoprazole. However, it is known that CBD can be metabolized by liver enzymes, particularly cytochrome P450. This same enzyme is responsible for the breakdown of other substances, including some medications. A possible interaction via cytochrome P450
In this context, there is a theoretical risk that CBD could affect the action or side effects of medications metabolized by cytochrome P450. Lansoprazole has been observed to be partially metabolized via this hepatic pathway.
Therefore, it is possible that the concomitant use ofCBD and lansoprazole
- could lead to a change in the elimination and/or activity of either of these compounds in the body. In practice, this could result in a decrease or increase in the effectiveness of the treatments, as well as the occurrence of potential adverse effects.
- Precautions to take when combining CBD and lansoprazole
- In the absence of concrete data on the interactions between CBD and lansoprazole, caution is advised when using these substances together. It is recommended to:
- Inform your doctor or pharmacist that you are taking CBD and lansoprazole so they can assess whether this combination poses a health risk;
Report any changes in your health to the healthcare professional responsible for monitoring your treatment;
Carefully follow the prescribed dosage and do not hesitate to seek advice if you have any doubts;
Be alert for signs of overdose or unusual side effects.
Therefore, although available information is still limited regarding the potential interaction between CBD and lansoprazole, it remains important to be vigilant and consult a healthcare professional before starting such a therapeutic combination.
