CBD (cannabidiol) is a substance derived from hemp. Known for its relaxing and pain-relieving effects, it is generating increasing interest among consumers and researchers. This raises the question: is CBD good for the liver? This article reviews the potential benefits of this molecule, as well as any precautions to take when consuming it. Therapeutic Potential of CBD on the Liver Anti-inflammatory Role
Scientific studies have highlighted the anti-inflammatory properties of cannabidiol.
This ability could be beneficial for the liver in certain cases, such as viral or autoimmune hepatitis. By reducing the inflammation caused by these conditions, CBD could contribute to the restoration of liver function and the prevention of potentially serious complications. Action on Liver FibrosisLiver fibrosis is a scarring process that occurs in response to various injuries to the liver. When this fibrosis becomes chronic, it can lead to irreversible destruction of liver cells and result in cirrhosis of the liver. However, some research suggests that CBD may have an antifibrotic effect by acting directly on the cells responsible for fibrosis production. This action could potentially slow down, or even stop, the progression to cirrhosis.
Improvement of symptoms of hepatorenal syndrome
CBD has also been studied in the treatment of hepatorenal syndrome, a serious complication that can affect patients with severe liver failure. Some preliminary results have shown that cannabidiol may help improve the clinical symptoms and biological parameters associated with this syndrome. Influence of CBD on liver enzymes The liver is an essential organ for the metabolism of medications and other chemicals in the body. Liver enzymes are notably involved in the elimination of CBD. Several studies have revealed that this molecule can interact with some of these enzymes, leading to changes in their activity.
Inducing or Inhibiting Effect
According to research, CBD can act as an inducer or an inhibitor of certain liver enzymes. In other words, it can increase or decrease their activity. These interactions can affect the metabolism and elimination of medications, altering their concentration in the blood and their effects.
Consequences for Drug Treatments
Consuming CBD can therefore be a concern for people undergoing drug treatments, particularly those metabolized by the liver. In some cases, the interaction of cannabidiol with liver enzymes could
increase the toxicity
of a medication or decrease its effectiveness . It is therefore recommended to consult a healthcare professional before consuming CBD while undergoing any specific treatment. Caution with prolonged use and high doses Despite the therapeutic potential mentioned above, it is important to exercise caution, especially with prolonged use and high doses of CBD. Some studies have shown that high doses of cannabidiol can cause liver damage in animals. However, these results are not necessarily applicable to humans. Importance of medical supervision
This nevertheless underscores the importance of medical supervision.
In the case of long-term use or substantial amounts of CBD, regular liver function tests are recommended to monitor liver function, particularly by measuring liver enzyme levels in the blood. Dosage adjustments may be necessary. Caution for at-risk individuals Individuals with pre-existing liver disease or a genetic predisposition to liver disease should exercise caution regarding CBD consumption. It is advisable to consult a healthcare professional to determine if using this molecule is appropriate and safe for their specific situation.Summary: CBD and the liver, what’s the verdict?
In short, while studies suggest that CBD may offer some benefits for the liver, there are also concerns about its influence on liver enzymes and the potential negative effects of prolonged use or high doses. Caution is therefore advised, and it is essential
to inform and consult healthcare professionals before consuming cannabidiol, especially for people at risk or undergoing medical treatment. Further research is needed to better understand the mechanisms of action of CBD and to definitively determine its effects on liver health.
