Research on cannabinoids is progressing. New ones are being discovered regularly and are being used in various sectors, including food and cosmetics. Regarding the latter, one question remains: cannabinoids be absorbed through the skin ? Let's explore this in detail below!
The summary
- Cannabinoids: methods of application to the skin
- Benefits of cannabinoids for dermatological disorders
Cannabinoids: methods of application to the skin
When you visit a CBD, like CBD.FR, to buy a cannabinoid product for topical application, you naturally have many questions. One is whether the cannabinoids in the product penetrate the skin. Another is which way they travel after penetration.
Strictly speaking, cannabinoids can sometimes penetrate your skin, and sometimes they can't. Confused? That's understandable! Let us explain. It all depends on how the product is applied, as indicated by the manufacturer. That said, at the time of writing, we identified two main methods.
On the one hand, there'stopical application. What is it? It's the method used for products like creams, ointments, and other cosmetics intended to be massaged into the epidermis (the upper layers of the skin). As you might have guessed, with this method, the cannabinoids remain on the surface. In other words, they are neither transported into the bloodstream nor into the dermis below.
On the other hand, there'stransdermal application. What are we referring to? This is the other application method, the complete opposite of the previous one (above). Here, the cannabinoids are delivered in a way that allows them to penetrate the upper layers of the skin and reach the bloodstream. The products typically used for this method are gels. Studies* show that CBD, when administered via a transdermal gel, easily enters the bloodstream and increases plasma levels of the cannabinoid.
Following the same pattern as CBD, THC appears to behave similarly. At least, that's what this article suggests. According to the article,transdermal application of delta-8-THC (a more stable form than delta-9-THC) provides better delivery of the cannabinoid into the bloodstream within 24 hours.
Based on the above, cannabinoids can be absorbed through the skin, specifically in the case of transdermal application. Although research in this area is relatively limited, it remains a good way to bypass the digestive system and deliver cannabinoids directly into the bloodstream.
Since we are talking about skin, it would be interesting to focus on thecontribution of cannabinoids, in relation to certain dermatological problems.
Benefits of cannabinoids for dermatological disorders
Indeed, given the long list of cannabinoids, we cannot proceed on a case-by-case basis. In other words, we cannot examine these molecules one by one to demonstrate their contribution to resolving specific dermatological problems. Instead, we will focus on: firstly, highlighting some research findings, and secondly, reviewing CBD products specifically designed for this type of issue.
Indeed, many studies focus on the effects of cannabinoids on various dermatological conditions. Let's look at a few examples. First, there's this study** published in the Journal of Dermatological Science. It reports on the effects of these molecules against keratinocyte hyperproliferation (which is associated with red, flaky, and scaly skin). In this condition, the immune system attacks healthy skin cells. As a result, skin cells accumulate on the skin's surface. Along these lines, this study highlights that THC, CBN, CBD, and CBG could inhibit this keratinocyte production and help the skin regain its balance.
On the other hand, there's this research*** published in The Journal of Clinical Investigation. It tests the effects of CBD on human sebocytes, cells that extract excess sebum. The result? Cannabinoids could help these cells function normally by acting on TRPV4 and A2A receptors.
Now that we have reviewed these two studies/research related to the contribution of cannabinoids for dermatological disorders, let's focus on some related products offered by CBD.FR.
For more products to solve certain dermatological problems, we suggest you consult our category dedicated to CBD cosmetics.
References:
- *ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
- **sciencedirect.com/science/article/abs/pii/S092318110600315X
- ***ncbi.nlm.nih.gov/pmc/articles/PMC4151231/
- ****sciencedirect.com/science/article/pii/037851738890052X
Co-founder of CBD.fr
Julien Cordobes is the editor of CBD.fr. Born in 1978 in the Paris region, he first trained in e-commerce before turning to natural health approaches, a dual perspective that now structures his way of writing about cannabidiol: reading the scientific literature as it is, without hardening the conclusions, and presenting it in a language that everyone understands.
He discovered CBD at a time when the French market was developing faster than the information available to it. He acquired CBD.fr in 2022 and then took on editorial responsibility for the blog. Since then, he has published numerous articles covering the daily use of CBD, the interpretation of laboratory analyses, the evolution of the legal framework, and precautions for use.
